Optical Activity

Enantiomerism

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In Pharmaceutical Chemistry, Enantiomerism is vital because the human body is a chiral environment composed of chiral building blocks like L-amino acids and D-sugars. Consequently, the body treats mirror-image drug molecules very differently. Definition Enantiomerism is a type of optical isomerism where molecules lack an internal plane of symmetry. It is vital concept because most … Read more

Optical Activity

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Optical activity is the ability of a substance to rotate the plane of Plane Polarized Light (PPL). This occurs in molecules that contain a chiral center (a carbon atom bonded to four different groups). This phenomenon is a cornerstone of stereochemistry and is vital in pharmaceutical analysis for identifying drugs and checking their purity. The … Read more