Pharmaceutical Organic Chemistry
Reactions of chiral molecules
Chemistry on a 2D chalkboard is a lie. Real life—and real medicine—happens in 3D. When we talk about the reactions of chiral molecules, we…
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Pharmaceutical Organic Chemistry
Asymmetric synthesis: partial and absolute
Nature doesn’t like symmetry. Our bodies are built of ‘left-handed’ amino acids and ‘right-handed’ sugars and is essentially a giant chiral environment. Everything from…
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Racemic modification and resolution methods
Introduction: Why Should Pharmacy Care? In pharmacy, we are not just dealing with chemicals — we are dealing with molecules that interact with the…
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Meso compounds
Understanding stereochemistry isn’t just about passing an exam. It’s about understanding how drugs interact with the body. Some molecules are like “chemical illusions,” and…
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Diastereoisomerism
In the world of chemistry, molecules can be like twins. Sometimes they are perfect mirror images (Enantiomers), and sometimes they are related but not…
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Elements of symmetry
Symmetry is the balanced arrangement of atoms in a molecule. In Pharmaceutical Chemistry, a molecule’s elements of symmetry tells us if a drug is…
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Stereochemistry Nomenclature Systems
Stereochemistry can feel like learning three different “languages” to describe the same object. There are different stereochemistry nomenclature system for organic compounds. One language…
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DL system of nomenclature
The D/L system (also known as the Fischer-Rosanoff convention) is one of the oldest method used to designate the configuration of optical isomers. While…
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RS system of nomenclature
It is the standard nomenclature used to describe the absolute configuration of a chiral center (usually a carbon atom) in a molecule. To talk…
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